AMMF006-11 [Monoclonal Antibody]
CD8A/B Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   IP FC
Immunogen Range:   Native purified CD8 from leukocytes of a patient suffering from a LGL-type leukemia
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   925/926
Swiss Prot:   P01732/P10966
Synonyms:   CD8, Leu2, MAL, p32
Purification:   Affinity purification
Storage:   Store at 4°C. For long term storage store at -20°C in PBS pH 7.4 (15 mM sodium azide). Avoid freeze/thaw cycles.
Background:   The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Caculated MW:   32 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information