AMM10381-11
[Monoclonal Antibody]
TUBB3 Mouse Monoclonal Antibody
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Species: |
Mouse |
Applications: |
WB IHC IF ICC |
Immunogen Range: |
A synthetic peptide (conjugated with KLH) corresponding to amino acids 441-448 of human TUBB3 |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG1 |
GENE ID: |
10381 |
Swiss Prot: |
Q13509 |
Synonyms: |
MC1R, TUBB4, beta-4 |
Purification: |
Affinity purification |
Storage: |
Store at 4°C. For long term storage store at -20°C in PBS pH 7.4 (15 mM sodium azide). Avoid freeze/thaw cycles. |
Background: |
The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin is required to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competitive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins |
Caculated MW: |
55 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!