AMM4684-11
[Monoclonal Antibody]
NCAM1 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | IHC IP FC |
| Immunogen Range: | Native purified NCAM1 from human acute myelogenous leukemia cell line KG-1 |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG2a |
| GENE ID: | 4684 |
| Swiss Prot: | P13591 |
| Synonyms: | CD56, MSK39, NCAM |
| Purification: | Affinity purification |
| Storage: | Store at 4°C in PBS, pH 7.4 (15 mM sodium azide). Do not freeze. |
| Background: | NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains (1). NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma (2). CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 (3). |
| Caculated MW: | 120-220 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information