AMM1021-11 [Monoclonal Antibody]
CDK6 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA
Immunogen Range:   A recombinant protein corresponding to full length human CDK6
Clonality:   Monoclonal Antibody
Isotype:   IgG2b Kappa
GENE ID:   1021
Swiss Prot:   Q00534
Synonyms:   MGC59692, PLSTIRE, STQTL11
Purification:   Affinity purification
Storage:   Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide). Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. [provided by RefSeq
Caculated MW:   36 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information