AMM4582-1C [Monoclonal Antibody]
MUC1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   ELISA
Immunogen Range:   Native purified human MUC1
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   4582
Swiss Prot:   P15941
Synonyms:   CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM
Purification:   Affinity purification
Storage:   Store at 4°C PBS, pH 7.4 (0.1% sodium azide).
Background:   This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq
Caculated MW:   230,400 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information