AMM3630-16 [Monoclonal Antibody]
INS Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   ELISA
Immunogen Range:   Native purified human INS
Clonality:   Monoclonal Antibody
Isotype:   IgG1 Kappa
GENE ID:   3630
Swiss Prot:   P01308
Synonyms:   ILPR, IRDN, IDDM2, MODY10, Insulin
Purification:   Affinity purification
Storage:   Store at -80°C PBS, pH 7.4 (0.1% sodium azide).Avoid freeze/thaw cycles.
Background:   After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
Caculated MW:   6 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information