ARP113878-11 [Polyclonal Antibody]
DTX2 Rabbit Polyclonal Antibody
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Species:   Mouse
Applications:   WB
Immunogen Range:   DTX2 (NP_0659431, 1 aa ~ 622 aa) full-length human protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   113878
Swiss Prot:   Q86UW9
Synonyms:   KIAA1528, MGC71098, RNF58
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   Deltex (DTX) encodes a putative E3 ubiquitin ligase first identified from Drosophila and shown to modulate Notch signaling. Several mammalian Deltex homologs have been isolated, all containing a pair of WWE repeats, a proline-rich region, and a Ring-finger domain. Deltex binds to the ankyrin-repeat domain of Notch and is capable of regulating Notch signaling positively or negatively in different systems. In addition, Deltex can also form homo-multimers. While Deltex has been implicated in Notch signaling regulation of lymphocyte development, this signal modifier may also have a transcriptional function independent of Notch.
Caculated MW:   67.20 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information