ARM64236-11
[Monoclonal Antibody]
PDLIM2 Rabbit Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species: |
Rabbit |
Applications: |
WB ELISA |
Immunogen Range: |
A synthetic peptide of human PDLIM2 is used for rabbit immunization |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG |
GENE ID: |
64236 |
Swiss Prot: |
Q96JY6 |
Synonyms: |
FLJ34715, MYSTIQUE, SLIM |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
PDLIM2, also known as Mystique, contains an amino-terminal PDZ domain and a carboxy-terminal LIM domain. PDLIM2 was orginally found to be associated with cytoskeletal proteins in epithelial cells to promote cell attachment and migration. Subsequent studies have shown that PDLIM2 can also inhibit NF-κB activity by acting as a nuclear ubiquitin E3 ligase for p65. PDLIM2 is suppressed in cancer cell lines by DNA methylation. Expression of PDLIM2 can inhibit anchorage-independent growth and tumor formation. |
Caculated MW: |
37.50 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!