AMM4292-12 [Monoclonal Antibody]
MLH1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC S-ELISA ELISA IF PLA
Immunogen Range:   MLH1 (AAH06850, 1 aa ~ 756 aa) full-length recombinant protein with GST tag
Clonality:   Monoclonal Antibody
Isotype:   IgG2a Kappa
GENE ID:   4292
Swiss Prot:   P40692
Synonyms:   COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
Caculated MW:   85 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information