AMP29882-11 [Polyclonal Antibody]
ANAPC2 Mouse Polyclonal Antibody
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Species:   Mouse
Applications:   WB
Immunogen Range:   ANAPC2 (AAH32503, 1 aa ~ 822 aa) full-length human protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   29882
Swiss Prot:   Q9UJX6
Synonyms:   APC2, RP11-350O14.5
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.
Caculated MW:   100 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information