AMP27123-11
[Polyclonal Antibody]
DKK2 Mouse Polyclonal Antibody
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Species: |
Mouse |
Applications: |
WB |
Immunogen Range: |
DKK2 (ADR828891, 1 aa ~ 259 aa) full-length human protein |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
27123 |
Swiss Prot: |
Q9UBU2 |
Synonyms: |
DKK-2 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). |
Caculated MW: |
28, 32 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!