ARM26469-11
[Monoclonal Antibody]
PTPN18 Rabbit Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: |
Rabbit |
| Applications: |
WB ELISA |
| Immunogen Range: |
A synthetic peptide of human PTPN18 is used for rabbit immunization |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
26469 |
| Swiss Prot: |
Q99952 |
| Synonyms: |
BDP1, PTP-HSCF |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. |
| Caculated MW: |
48 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!