AMM23411-13 [Monoclonal Antibody]
SIRT1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB S-ELISA ELISA
Immunogen Range:   SIRT1 (AAH12499, 456 aa ~ 555 aa) partial recombinant protein with GST tag
Clonality:   Monoclonal Antibody
Isotype:   IgG1 Kappa
GENE ID:   23411
Swiss Prot:   Q96EB6
Synonyms:   SIR2L1
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Caculated MW:   120 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information