AMM10411-11 [Monoclonal Antibody]
RAPGEF3 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Mouse
Applications:   WB S-ELISA ELISA
Immunogen Range:   RAPGEF3 (AAH17728, 772 aa ~ 881 aa) partial recombinant protein with GST tag
Clonality:   Monoclonal Antibody
Isotype:   IgG2a Kappa
GENE ID:   10411
Swiss Prot:   O95398
Synonyms:   CAMP-GEFI, EPAC, EPAC1, HSU79275, MGC21410, bcm910
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signaling in part through protein kinase A (PKA). EPAC signaling plays a significant role in a number of cellular processes including migration and focal adhesion formation, exocytosis, insulin signaling, axon growth and guidance and neurotransmitter release.
Caculated MW:   100 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information