AMP10015-11 [Polyclonal Antibody]
PDCD6IP Mouse Polyclonal Antibody
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Species:   Mouse
Applications:   WB IF
Immunogen Range:   PDCD6IP (NP_037506, 1 aa ~ 868 aa) full-length human protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   10015
Swiss Prot:   Q8WUM4
Synonyms:   AIP1, Alix, DRIP4, HP95, MGC17003
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Caculated MW:   95.48 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information