ARP10010-12 [Polyclonal Antibody]
TANK Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   TANK (NP_5978411, 1 aa ~ 119 aa) full-length human protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   10010
Swiss Prot:   Q92844
Synonyms:   I-TRAF, TRAF2
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene.
Caculated MW:   50 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information