AMM9759-11
[Monoclonal Antibody]
HDAC4 Mouse Monoclonal Antibody
www.yhsbio.com
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| Species: |
Mouse |
| Applications: |
WB IHC S-ELISA ELISA IF |
| Immunogen Range: |
HDAC4 (NP_0060281, 551 aa ~ 648 aa) partial recombinant protein with GST tag |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgG2a Kappa |
| GENE ID: |
9759 |
| Swiss Prot: |
P56524 |
| Synonyms: |
HA6116, HD4, HDAC-A, HDACA, KIAA0288 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. |
| Caculated MW: |
140 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!