AMM7010-11
[Monoclonal Antibody]
TEK Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB ELISA |
| Immunogen Range: | TEK (NP_000450, 66 aa ~ 185 aa) partial recombinant protein with GST tag |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG2a Kappa |
| GENE ID: | 7010 |
| Swiss Prot: | Q02763 |
| Synonyms: | CD202B, TIE-2, TIE2, VMCM, VMCM1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: | The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. |
| Caculated MW: | 160 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information