
| Species: | Rabbit | 
| Applications: | WB FC IHC IF | 
| Immunogen Range: | KLH conjugated synthetic peptide derived from human IL-23 | 
| Clonality: | Polyclonal Antibody | 
| Isotype: | IgG | 
| GENE ID: | 51561 | 
| Swiss Prot: | Q9NPF7 | 
| Synonyms: | P19, SGRF, IL-23, IL-23A, IL23P19, Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19, IL23A, UNQ2498/PRO5798 | 
| Purification: | Purified by Protein A. | 
| Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Background: | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. | 
| Caculated MW: | / | 
| Observed MW: | Refer to Figures | 
| Applications: | 
                                WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 FC 1:20-1:100  | 
                        
| Reacitivity: | Human, Mouse, Rat |