ARP6237-11 [Polyclonal Antibody]
RRAS Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   RRAS (NP_0062611, 1 aa ~ 218 aa) full-length human protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   6237
Swiss Prot:   P10301
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   R-Ras, a member of the small GTPase family, is homologous to H-, K- and N-Ras, but does not activate MAP kinase pathways and is only weakly oncogenic. Instead, R-Ras is engaged in integrin activation. The effector loop and the carboxy-terminal proline-rich and prenylation sites of R-Ras are critical for integrin activation. Phosphorylation by EphB2 receptor tyrosine kinase and Src at Tyr66 of R-Ras suppresses integrin activity.
Caculated MW:   23.50 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information