AMM5591-11
[Monoclonal Antibody]
PRKDC Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB IHC S-ELISA ELISA IF |
| Immunogen Range: | PRKDC (NP_008835, 4019 aa ~ 4128 aa) partial recombinant protein with GST tag |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG2a Kappa |
| GENE ID: | 5591 |
| Swiss Prot: | P78527 |
| Synonyms: | DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: | The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
| Caculated MW: | 450 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information