AMP5524-11 [Polyclonal Antibody]
PPP2R4 Mouse Polyclonal Antibody
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Species:   Mouse
Applications:   WB IF
Immunogen Range:   PPP2R4 (NP_0669542, 1 aa ~ 323 aa) full-length human protein
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   5524
Swiss Prot:   Q15257
Synonyms:   MGC2184, PP2A, PR53, PTPA
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Caculated MW:   35.53 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information