AMM5460-13
[Monoclonal Antibody]
POU5F1 Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Mouse |
| Applications: | WB ELISA |
| Immunogen Range: | POU5F1 (AAH20712, 81 aa ~ 164 aa) partial recombinant protein with GST tag |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG2b Kappa |
| GENE ID: | 5460 |
| Swiss Prot: | Q01860 |
| Synonyms: | MGC22487, OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: | This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. |
| Caculated MW: | 18.3 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information