AMM5430-12
[Monoclonal Antibody]
POLR2A Mouse Monoclonal Antibody
www.yhsbio.com
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support@yhsbio.com
+86-21-54651191
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DATASHEET
Species: |
Mouse |
Applications: |
WB S-ELISA ELISA |
Immunogen Range: |
POLR2A (NP_000928, 1 aa ~ 110 aa) partial recombinant protein with GST tag |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG2b Kappa |
GENE ID: |
5430 |
Swiss Prot: |
P24928 |
Synonyms: |
MGC75453, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq |
Caculated MW: |
250 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!