ARM5130-11
[Monoclonal Antibody]
PCYT1A Rabbit Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB ELISA |
| Immunogen Range: | A synthetic peptide of human PCYT1A is used for rabbit immunization |
| Clonality: | Monoclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 5130 |
| Swiss Prot: | P49585 |
| Synonyms: | CT, CTPCT, PCYT1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: | CTP:phosphocholine cytidylyltransferase (CCT) is a critical enzyme that regulates the CDP-choline pathway for the biosynthesis of phosphatidylcholine. Three distinct CCT isoforms are found in mammals, including CCTα, CCTβ2, and CCTβ3. CCTα is the major isoform that is expressed in most tissues. CCTα is essential in the synthesis and secretion of surfactant by alveolar epithelial cells and is important in maintaining the phosphatidylcholine level that regulates lipoprotein assembly and secretion in hepatocytes. CCTα is a major component in membrane biogenesis during cytokine secretion by stimulated macrophages. Monoubiquitination of CCTα prevents it from entering the nucleus and leads to its degradation by lysosome. |
| Caculated MW: | 41.7 kDa |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information