AMP5111-11
[Polyclonal Antibody]
PCNA Mouse Polyclonal Antibody
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Species: |
Mouse |
Applications: |
WB IF |
Immunogen Range: |
PCNA (NP_0025831, 1 aa ~ 261 aa) full-length human protein |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
5111 |
Swiss Prot: |
P12004 |
Synonyms: |
MGC8367 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
Caculated MW: |
36 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!