AMP5111-11
[Polyclonal Antibody]
PCNA Mouse Polyclonal Antibody
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DATASHEET
| Species: |
Mouse |
| Applications: |
WB IF |
| Immunogen Range: |
PCNA (NP_0025831, 1 aa ~ 261 aa) full-length human protein |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
5111 |
| Swiss Prot: |
P12004 |
| Synonyms: |
MGC8367 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
| Caculated MW: |
36 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!