AMM5071-11 [Monoclonal Antibody]
PARK2 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB S-ELISA ELISA IF
Immunogen Range:   PARK2 (AAH22014, 288 aa ~ 387 aa) partial recombinant protein with GST tag
Clonality:   Monoclonal Antibody
Isotype:   IgG3 Kappa
GENE ID:   5071
Swiss Prot:   O60260
Synonyms:   AR-JP, LPRS2, PDJ, PRKN
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Caculated MW:   50 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information