ARP4782-11
[Polyclonal Antibody]
NFIC Rabbit Polyclonal Antibody
www.yhsbio.com
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
NFIC (NP_0055882, 1 aa ~ 428 aa) full-length human protein |
Clonality: |
Polyclonal Antibody |
Isotype: |
/ |
GENE ID: |
4782 |
Swiss Prot: |
P08651 |
Synonyms: |
CTF, CTF5, MGC20153, NF-I, NFI |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
NFI-C belongs to the nuclear factor I (NFI) family of site-specific transcription factors that regulate viral DNA replication and expression of various genes. The NFI family is composed of four members in vertebrates: NFI-A, NFI-B, NFI-C, and NFI-X, all of which are critical in the development of multiple organ systems in mice and humans. NFI-C is expressed in various tissues and regulates TGF-β dependent tooth development and hair follicle cycling. Research studies have shown that NFI-C directly represses FoxF1 transcription and suppresses the motility and invasiveness of breast cancer cells. |
Caculated MW: |
55-65 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!