AMM4744-15
[Monoclonal Antibody]
NEFH Mouse Monoclonal Antibody
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DATASHEET
Species: |
Mouse |
Applications: |
WB S-ELISA ELISA |
Immunogen Range: |
NEFH (NP_066554, 263 aa ~ 363 aa) partial recombinant protein with GST tag |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG2a Kappa |
GENE ID: |
4744 |
Swiss Prot: |
P12036 |
Synonyms: |
NFH |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |
Caculated MW: |
180-220 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!