AMM3932-13 [Monoclonal Antibody]
LCK Mouse Monoclonal Antibody
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Species:   Rabbit
Applications:   WB PLA
Immunogen Range:   LCK (AAH132001, 1 aa ~ 539 aa) full-length human protein
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   3932
Swiss Prot:   P06239
Synonyms:   LSK, YT16, p56lck, pp58lck
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.
Caculated MW:   56 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information