ARM3350-11 [Monoclonal Antibody]
HTR1A Rabbit Monoclonal Antibody
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Species:   Rabbit
Applications:   WB ELISA
Immunogen Range:   A synthetic peptide of human HTR1A is used for rabbit immunization
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   3350
Swiss Prot:   P08908
Synonyms:   5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   Serotonin (5-hydroxytryptamine/5-HT) is a monoamine found in the central nervous system. Serotonin receptors are mostly members of the G Protein-Coupled Receptor (GPCR) superfamily. GPCRs are a family of cell surface receptors containing seven transmembrane proteins. GPCRs activate signal transduction pathways and cyclic AMP formation. Seven subclasses of serotonin receptors (5-HTR) have been described (5-HTR1-7). There are five subclasses of 5-HTR1 (1A, 1B, 1D, 1E, and 1F). 5-HTR1A is an inhibitory GPCR expressed both in serotonergic neurons and in target areas receiving serotonergic innervation. These receptors are associated with depression, anxiety, and the response to antidepressants.
Caculated MW:   80-240 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information