AMM2904-11
[Monoclonal Antibody]
GRIN2B Mouse Monoclonal Antibody
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Species: |
Mouse |
Applications: |
WB S-ELISA ELISA PLA |
Immunogen Range: |
GRIN2B (NP_000825, 127 aa ~ 236 aa) partial recombinant protein with GST tag |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgG2a Kappa |
GENE ID: |
2904 |
Swiss Prot: |
Q13224 |
Synonyms: |
MGC142178, MGC142180, NMDAR2B, NR2B, hNR3 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Background: |
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. |
Caculated MW: |
190 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!