AMP2627-11 [Polyclonal Antibody]
GATA6 Mouse Polyclonal Antibody
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Species:   Mouse
Applications:   WB ELISA
Immunogen Range:   GATA6 (NP_005248, 496 aa ~ 595 aa) partial recombinant protein with GST tag
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   2627
Swiss Prot:   Q92908
Synonyms:   /
Purification:   Affinity purification
Storage:   Store at -20°C or lower in 50% glycerol. Avoid freeze/thaw cycles.
Background:   GATA proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA binding domains, which bind directly to the nucleotide sequence core element GATA. There are six vertebrate GATA proteins, designated GATA-1 to GATA-6. GATA-6 plays a critical role in endoderm development. It is essential for development of the heart, gut, and other organs. Knock out of GATA-6 is embryonic lethal due to defects in formation of the heart tube and a failure to develop extraembryonic endoderm. Loss of expression, or loss of nuclear localization of GATA-6 is apparent in a large number of ovarian tumors.
Caculated MW:   55 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information