AMM2029-11 [Monoclonal Antibody]
ENSA Mouse Monoclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Mouse
Applications:   WB ELISA
Immunogen Range:   ENSA (AAH00436, 1 aa ~ 121 aa) full-length recombinant protein with GST tag
Clonality:   Monoclonal Antibody
Isotype:   IgG2a Kappa
GENE ID:   2029
Swiss Prot:   O43768
Synonyms:   MGC4319, MGC78563, MGC8394
Purification:   Affinity purification
Storage:   Store at -20°C or lower in ascites fluid. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Caculated MW:   15 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information