AMP1107-11 [Polyclonal Antibody]
CHD3 Mouse Polyclonal Antibody
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Species:   Mouse
Applications:   WB IF
Immunogen Range:   CHD3 (NP_001005273, 1654 a.a. ~ 1741 a.a) partial recombinant protein with GST tag
Clonality:   Polyclonal Antibody
Isotype:   /
GENE ID:   1107
Swiss Prot:   Q12873-3
Synonyms:   Mi-2a, Mi2-ALPHA, ZFH
Purification:   Affinity purification
Storage:   Store at -20°C or lower in 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Caculated MW:   260 kDa
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information