AMP1107-11
[Polyclonal Antibody]
CHD3 Mouse Polyclonal Antibody
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| Species: |
Mouse |
| Applications: |
WB IF |
| Immunogen Range: |
CHD3 (NP_001005273, 1654 a.a. ~ 1741 a.a) partial recombinant protein with GST tag |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
/ |
| GENE ID: |
1107 |
| Swiss Prot: |
Q12873-3 |
| Synonyms: |
Mi-2a, Mi2-ALPHA, ZFH |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or lower in 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
| Caculated MW: |
260 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!