AMM842-12 [Monoclonal Antibody]
CASP9 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB S-ELISA ELISA IF PLA
Immunogen Range:   CASP9 (AAH024521, 1 aa ~ 416 aa) full-length recombinant protein with GST tag
Clonality:   Monoclonal Antibody
Isotype:   IgG1 kappa
GENE ID:   842
Swiss Prot:   P55211
Synonyms:   APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6
Purification:   Affinity purification
Storage:   Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Background:   This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.
Caculated MW:   47, 37, 35 kDa (H) 51, 39, 37 kDa (R,M)
Observed MW:   Refer to Figures
Applications:  
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information