ARP324-11
[Polyclonal Antibody]
APC Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | APC (AAI115921, 1 aa ~ 2843 aa) full-length human protein |
| Clonality: | Polyclonal Antibody |
| Isotype: | / |
| GENE ID: | 324 |
| Swiss Prot: | P25054 |
| Synonyms: | BTPS2, DP2, DP2.5, DP3, GS |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Background: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Caculated MW: | 160 kDa truncated APC in SW480 cells 310 kDa full-length APC |
| Observed MW: | Refer to Figures |
| Applications: | |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information