AMM32-11
[Monoclonal Antibody]
ACACB Mouse Monoclonal Antibody
www.yhsbio.com
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DATASHEET
| Species: |
Mouse |
| Applications: |
WB ELISA |
| Immunogen Range: |
ACACB (NP_001084, 22 aa ~ 120 aa) partial recombinant protein with GST tag |
| Clonality: |
Monoclonal Antibody |
| Isotype: |
IgM Kappa |
| GENE ID: |
32 |
| Swiss Prot: |
O00763 |
| Synonyms: |
ACC2, ACCB, HACC275 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or lower in ascites fluid. Avoid freeze/thaw cycles. |
| Background: |
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. |
| Caculated MW: |
280 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
|
| Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!