AMM32-11
[Monoclonal Antibody]
ACACB Mouse Monoclonal Antibody
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DATASHEET
Species: |
Mouse |
Applications: |
WB ELISA |
Immunogen Range: |
ACACB (NP_001084, 22 aa ~ 120 aa) partial recombinant protein with GST tag |
Clonality: |
Monoclonal Antibody |
Isotype: |
IgM Kappa |
GENE ID: |
32 |
Swiss Prot: |
O00763 |
Synonyms: |
ACC2, ACCB, HACC275 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or lower in ascites fluid. Avoid freeze/thaw cycles. |
Background: |
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. |
Caculated MW: |
280 kDa |
Observed MW: |
Refer to Figures |
Applications: |
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!