ARP4437-62
[Polyclonal Antibody]
MSH3 Rabbit Polyclonal Antibody
www.yhsbio.com
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human MSH3 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
4437 |
Swiss Prot: |
P20585 |
Synonyms: |
DUP, MRP1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5458% glycerol. Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. |
Caculated MW: |
127 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!