ARP471-61
[Polyclonal Antibody]
ATIC Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A recombinant protein of human ATIC |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
471 |
| Swiss Prot: |
P31939 |
| Synonyms: |
PURH, AICAR, AICARFT, IMPCHASE |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 6163% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. |
| Caculated MW: |
64 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!