ARP5984-61
[Polyclonal Antibody]
RFC4 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A recombinant protein of human RFC4 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
5984 |
| Swiss Prot: |
P35249 |
| Synonyms: |
A1, RFC37 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5854% glycerol. Avoid freeze/thaw cycles. |
| Background: |
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. |
| Caculated MW: |
39 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!