ARP5199-61
[Polyclonal Antibody]
CFP Rabbit Polyclonal Antibody
www.yhsbio.com
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support@yhsbio.com
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human CFP |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
5199 |
Swiss Prot: |
P27918 |
Synonyms: |
BFD, PFC, PFD, PROPERDIN |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 6009% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Caculated MW: |
51 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!