ARP5732-63
[Polyclonal Antibody]
PTGER2 Rabbit Polyclonal Antibody
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DATASHEET
Species: |
Rabbit |
Applications: |
WB |
Immunogen Range: |
A recombinant protein of human PTGER2 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
5732 |
Swiss Prot: |
P43116 |
Synonyms: |
EP2 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5870% glycerol. Avoid freeze/thaw cycles. |
Background: |
This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. Prostaglandin E2 receptor (53kDa), also known as EP2, is a prostaglandin receptor for prostaglandin E2. It is encoded by the human gene PTGER2. Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. |
Caculated MW: |
40 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!