ARP1910-61 [Polyclonal Antibody]
EDNRB Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide of human EDNRB
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1910
Swiss Prot:   P24530
Synonyms:   ETB,ET-B,ETBR,ETRB,HSCR,WS4A,ABCDS,ET-BR,HSCR2
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5997% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Caculated MW:   50 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information