ARP2775-61
[Polyclonal Antibody]
GNAO1 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human GNAO1 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
2775 |
Swiss Prot: |
P09471 |
Synonyms: |
GNAO, EIEE17, G-ALPHA-o |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively. |
Caculated MW: |
40 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!