Species: | Rabbit |
Applications: | WB IHCIF IP |
Immunogen Range: | A recombinant protein of mouseMIWI |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 57749 |
Swiss Prot: | Q9JMB7 |
Synonyms: | Piwil1, Miwi, PIWIL1 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | The Drosophila piwi gene was identified as being required for the self-renewal of germline stem cells (1). Piwi homologs are well conserved among various species including Arabidopsis, C. elegans, and Homo sapiens (1). Both Miwi and Mili proteins are mouse homologs of Piwi and contain a C-terminal Piwi domain (2). Miwi and Mili bind to Piwi-interacting RNAs (piRNAs) in male germ cells and are essential for spermatogenesis in mice (3-5). |
Caculated MW: | 99 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:100 |
Reacitivity: | Mouse, Rat |