ARP4318-63
[Polyclonal Antibody]
MMP9 Rabbit Polyclonal Antibody
www.yhsbio.com
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support@yhsbio.com
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DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptideof human MMP9 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
4318 |
Swiss Prot: |
P14780 |
Synonyms: |
CLG4B, GELB, MMP-9 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5). |
Caculated MW: |
78 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!