Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human CSAD |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 51380 |
Swiss Prot: | |
Synonyms: | CSAD, CSAD_HUMAN, CSD, Cysteine sulfinic acid decarboxylase, Cysteine-sulfinate decarboxylase, Sulfinoalanine decarboxylase. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |