ARP650-62
[Polyclonal Antibody]
BMP2 Rabbit Polyclonal Antibody
www.yhsbio.com
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support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A recombinant protein of human BMP2 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
650 |
Swiss Prot: |
P12643 |
Synonyms: |
bmp2, BMP 2A, BMP 2, BMP2A, bone morphogenetic protein 2,Bonemorphogenetic protein 2A |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation (1,2). BMPs are synthesized as precursor proteins that are processed by cleavage to produce mature proteins. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting in the translocation of Smad to the nucleus. BMP was also reported to activate MAPK pathways in some systems (3,4). |
Caculated MW: |
44 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!