Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | KLH conjugated synthetic peptide derived from human PPT2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | |
Swiss Prot: | |
Synonyms: | Lysosomal thioesterase PPT2, Palmitoyl protein hydrolase 2, Palmitoyl protein thioesterase 2, PPT 2, PPT-2, Ppt2, PPT2_HUMAN, S thioesterase G14, S-thioesterase G14. |
Purification: | Purified by Protein A. |
Storage: | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Background: | PPT2 (palmitoyl-protein thioesterase 2), also known as G14, is a 302 amino acid glycosylated protein that localizes to the lysosome and belongs to the palmitoyl-protein thioesterase family. Expressed throughout the body with highest levels in skeletal muscle, PPT2 functions to remove thioester-linked fatty acyl groups from a variety of substrates, including S-palmitoyl-CoA, thereby playing an important role in lipid metabolism. PPT2 operates at an optimal pH of 7 and exhibits the highest activity for the acyl groups on myristic and palmitic acids, with lower levels of activity toward other short- and long-chain acyl substrates. PPT2 exists as two isoforms, one of which is expressed at low levels and is catalytically inactive. |
Caculated MW: | / |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:100-1:500 IF 1:50-1:200 |
Reacitivity: | Human, Mouse, Rat |